Population genetics of Glossina fuscipes fuscipes from southern Chaduse asterix (*) to get italics

Sophie Ravel, Mahamat Hissène Mahamat, Adeline Ségard, Rafael Argiles-Herrero, Jérémy Bouyer, Jean-Baptiste Rayaisse, Philippe Solano, Brahim Guihini Mollo, Mallaye Pèka, Justin Darnas, Adrien Marie Gaston Belem, Wilfrid Yoni, Camille Noûs, Thierry de MeeûsPlease use the format "First name initials family name" as in "Marie S. Curie, Niels H. D. Bohr, Albert Einstein, John R. R. Tolkien, Donna T. Strickland"

2023

<p>In Subsaharan Africa, tsetse flies (genus Glossina) are vectors of trypanosomes causing Human African Trypanosomiasis (HAT) and Animal African Trypanosomosis (AAT). Some foci of HAT persist in Southern Chad, where a program of tsetse control was started against the local vector Glossina fuscipes fuscipes in the Mandoul focus in 2014, and in Maro in 2018. Flies were also sampled in 2018 in Timbéri and Dokoutou. We analyzed the population genetics of G. fuscipes fuscipes from the four tsetse-infested zones. The trapping samples were characterized by a strong female biased sex-ratio, except in Timbéri and Dokoutou that had high tsetse densities. Apparent density and effective population density appeared smaller in the main foci of Mandoul and Maro and the average dispersal distance (within the spatial scale of each zone) was as large as or larger than the total length of each respective zone. The genetic signature of a population bottleneck was found in the Mandoul and Timbéri area, suggesting a large ancient interconnected metapopulation that underwent genetic subdivision into small, isolated pockets due to adverse environmental conditions. The long-range dispersal and the existence of genetic outliers suggest a possibility of migration from remote sites such as the Central African Republic in the south (although the fly situation remains unknown there) and/or a genetic signature of recent exchanges. Due to likely isolation, an eradication strategy may be considered for sustainable HAT control in Mandoul focus. Another strategy will probably be required in Maro focus, which probably experiences much more exchanges with its neighbors.&nbsp;</p>

https://zenodo.org/record/7711195You should fill this box only if you chose 'All or part of the results presented in this preprint are based on data'. URL must start with http:// or https://

https://zenodo.org/record/7711195You should fill this box only if you chose 'Scripts were used to obtain or analyze the results'. URL must start with http:// or https://

Tsetse flies, Dispersal, Trypanosomosis, Control

NonePlease indicate the methods that may require specialised expertise during the peer review process (use a comma to separate various required expertises).

Biology, Ecology, Evolution, Genetics/Genomics, Insecta, Medical entomology, Parasitology, Pest management, Veterinary entomology

Johnson O. Ouma, [joouma@gmail.com], Helliot S. Krafsur, [ekrafsur@iastate.edu], Gustave Simo, [gsimoca@yahoo.fr], Christophe Rogier, [christophe.rogier@wanadoo.fr], Chantel J. De Beer, [debeerc@arc.agric.za], Claire Garros, [claire.garros@cirad.fr], Charles D. Criscione, [ccriscione@bio.tamu.edu], Norah Saarman, [norah.saarman@yale.edu], Abraham Mayoke, [demichbra@gmail.com], Benjamin Rosenthal, [benjamin.rosenthal@usda.gov] No need for them to be recommenders of PCI Zool. Please do not suggest reviewers for whom there might be a conflict of interest. Reviewers are not allowed to review preprints written by close colleagues (with whom they have published in the last four years, with whom they have received joint funding in the last four years, or with whom they are currently writing a manuscript, or submitting a grant proposal), or by family members, friends, or anyone for whom bias might affect the nature of the review - see the code of conduct

2022-04-22 11:25:24

Michael Lattorff

Audrey Bras